Analytic Review: Disorders of Phagocyte Function

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Analytic Review : Disorders of Phagocyte Function

R ECENT CLINICAL AND LABORATORY INVESTIGATIONS have led to the description of a group of syndromes related to impaired bactericidal functions of neutrophils and monocytes.13 Although the pathophysiology of this group of disorders is unknown, detailed immunologic, biochemical and morphologic studies have elucidated some clues to the basic defects leading to impairment of phagocyte function. The ...

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Analytic review: disorders of phagocyte function.

R ECENT CLINICAL AND LABORATORY INVESTIGATIONS have led to the description of a group of syndromes related to impaired bactericidal functions of neutrophils and monocytes.13 Although the pathophysiology of this group of disorders is unknown, detailed immunologic, biochemical and morphologic studies have elucidated some clues to the basic defects leading to impairment of phagocyte function. The ...

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Analytic Review : Disorders of Phagocyte Function

R ECENT CLINICAL AND LABORATORY INVESTIGATIONS have led to the description of a group of syndromes related to impaired bactericidal functions of neutrophils and monocytes.13 Although the pathophysiology of this group of disorders is unknown, detailed immunologic, biochemical and morphologic studies have elucidated some clues to the basic defects leading to impairment of phagocyte function. The ...

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Analytic Review : Disorders of Phagocyte Function

R ECENT CLINICAL AND LABORATORY INVESTIGATIONS have led to the description of a group of syndromes related to impaired bactericidal functions of neutrophils and monocytes.13 Although the pathophysiology of this group of disorders is unknown, detailed immunologic, biochemical and morphologic studies have elucidated some clues to the basic defects leading to impairment of phagocyte function. The ...

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Chronic granulomatous disease and other disorders of phagocyte function.

The analysis of specific gene defects in disorders of phagocyte function has shed light on important aspects of the innate immune response. Each disorder has distinctive features in the clinical presentation and characteristic microbial pathogens. Chronic granulomatous disease has been extensively studied both in patient series and in mouse models. New insights continue to be obtained regarding...

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ژورنال

عنوان ژورنال: Blood

سال: 1970

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v35.6.851.851